Threonine

Threonine

SCHEMBL9838841

C[C@@H](O)[C@H](N)C(=O)O.O=C1NC(=O)C(c2ccccc2)N1

nearest known ligand 0.48

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.48
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
MAPK10 P53779 1/20 0.42
HSD17B10 Q99714 1/20 0.41
GAA P10253 1/20 0.40
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL9838836 1.00 USP2 (0.48) USP2TDP1ALDH1A1MAPTMAPK10
Threonine SCHEMBL7805410 0.87 ALDH1A1 (0.43) USP2TDP1ALDH1A1MAPTGAA
SCHEMBL19955179 0.79 TDP1 (0.66) USP2TDP1ALDH1A1MAPTMAPK10
SCHEMBL395878 0.79 TDP1 (0.66) USP2TDP1ALDH1A1MAPTMAPK10
SCHEMBL31738422 0.79 TDP1 (0.66) USP2TDP1ALDH1A1MAPTMAPK10
Cysteine SCHEMBL9128017 0.78 IDO1 (0.45) USP2TDP1ALDH1A1MAPTMAPK10
Cystine SCHEMBL440076 0.77 IDO1 (0.44) USP2TDP1ALDH1A1MAPTMAPK10
Threonine SCHEMBL11423702 0.76 SLC7A5 (0.34)
SCHEMBL9402119 0.75 USP2 (0.42) USP2TDP1ALDH1A1MAPTMAPK10
Alanine SCHEMBL891875 0.75 ALDH1A1 (0.48) USP2TDP1ALDH1A1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068187-A Culture of microorganisms to transform hydantoins to amino acids MITSUI TOATSU CHEMICALS, INC. (JP) 1991-11-26 US disclosed