SCHEMBL9838964

SCHEMBL9838964

C=CC(=O)N1C(C)(C)CC(OC(=O)C(CCCC)(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)OC2CC(C)(C)N(C(=O)C=C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.36
KMT2A Q03164 4/20 0.35
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
TSHR P16473 2/20 0.35
MAPK1 P28482 2/20 0.35
BLM P54132 2/20 0.35
ATM Q13315 2/20 0.35
HIF1A Q16665 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MAPT P10636 2/20 0.35
USP2 O75604 1/20 0.35
CYP2D6 P10635 1/20 0.35
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
GMNN O75496 1/20 0.32
GABBR2 O75899 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3425141 0.91 ALDH1A1 (0.40) GAAKMT2AALDH1A1MEN1CYP1A2
SCHEMBL11468979 0.91 GAA (0.36) GAAKMT2AALDH1A1MEN1CYP1A2
SCHEMBL13599617 0.88 KMT2A (0.34) GAAKMT2AALDH1A1MEN1CYP1A2
SCHEMBL7509051 0.88 GAA (0.36) GAAKMT2AALDH1A1MEN1CYP1A2
SCHEMBL31364 0.88 GAA (0.36) GAAKMT2AALDH1A1MEN1CYP1A2
SCHEMBL12933651 0.87 GAA (0.36) GAAKMT2AALDH1A1MEN1CYP1A2
SCHEMBL9591848 0.86 GAA (0.35) GAAKMT2AALDH1A1MEN1CYP1A2
SCHEMBL12897914 0.86 GAA (0.35) GAAKMT2AALDH1A1MEN1CYP1A2
SCHEMBL11461866 0.85
SCHEMBL9400316 0.84 TSHR (0.41) GAAKMT2AALDH1A1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257321-B1 IMPROVING WEATHERABILITY AND ADHERENCE OF POLYPROPYLENE ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-03-13 EP disclosed
US-4997888-A Tetramethyl piperidyl compound ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-03-05 US disclosed
US-4994529-A Surface activation with oxygen; piperidyl stabilizer and phenolic antioxidant present ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-02-19 US disclosed
US-4957954-A TETRAMETHYPIPERIDINYL COMPOUND AND PERCHLORATE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed
EP-0257321-A2 Improving weatherability and adherence of polypropylene ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-03-02 EP disclosed
EP-0212559-A2 Stabilizer compositions for polyvinyl chloride resins and stabilized polyvinyl chloride resin compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-03-04 EP disclosed