SCHEMBL3425141

SCHEMBL3425141

C=CC(=O)N1C(C)(C)CC(OC(=O)C(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C(=O)OC2CC(C)(C)N(C(=O)C=C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.40
KMT2A Q03164 5/20 0.40
TSHR P16473 4/20 0.40
MAPT P10636 4/20 0.40
MEN1 O00255 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 2/20 0.40
MAPK1 P28482 2/20 0.40
BLM P54132 2/20 0.40
ATM Q13315 2/20 0.40
HIF1A Q16665 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
USP2 O75604 1/20 0.40
CYP2D6 P10635 1/20 0.40
GAA P10253 8/20 0.38
LMNA P02545 3/20 0.36
ALOX15 P16050 2/20 0.36
GMNN O75496 1/20 0.36
GABBR2 O75899 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9838964 0.91 GAA (0.36) ALDH1A1KMT2ATSHRMAPTMEN1
SCHEMBL11520167 0.89 ALDH1A1 (0.40) ALDH1A1KMT2ATSHRMAPTMEN1
SCHEMBL11085415 0.89 ALDH1A1 (0.38) ALDH1A1KMT2ATSHRMAPTMEN1
SCHEMBL11523206 0.86 ALDH1A1 (0.38) ALDH1A1KMT2ATSHRMAPTMEN1
SCHEMBL9184058 0.85 ALDH1A1 (0.41) ALDH1A1KMT2ATSHRMAPTMEN1
SCHEMBL11519680 0.85 MEN1 (0.34) KMT2AMAPTMEN1
SCHEMBL11517489 0.85 GAA (0.38) ALDH1A1KMT2ATSHRMAPTMEN1
SCHEMBL11486096 0.85 ALDH1A1 (0.39) ALDH1A1KMT2ATSHRMAPTMEN1
SCHEMBL11517220 0.84 GAA (0.37) ALDH1A1KMT2ATSHRMAPTMEN1
SCHEMBL11521765 0.83 LMNA (0.40) ALDH1A1KMT2ATSHRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6437164-B1 REACTING BIPHENYL AND PHOSPHORUS TRICHLORIDE IN PRESENCE OF ALUMINUM CHLORIDE, ADDING PYRIDINE, RESULTING DICHLOROPHOSPHINE IS REACTED WITH A PHENOL, REMOVING FORMED PYRIDINE-ALUMINUM CHLORIDE COMPLEX YOSHITOMI FINE CHEMICALS, LTD. (JP) 2002-08-20 US claimed
EP-1142898-A1 PROCESS FOR THE PREPARATION OF PHOSPHONITE COMPOUNDS Yoshitomi Fine Chemicals, Ltd. (JP) 2001-10-10 EP claimed
US-5081170-A Polyolefin, phenolic antioxidant, light stabilizer, sulfur antioxidant, talc filler, weatherproofing ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1992-01-14 US claimed
US-4957953-A MONO-AND POLYTETRAMETHYLPIPERIDINE ESTERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US claimed
US-20200216752-A1 HYDROXYL-FUNCTIONAL UNSATURATED POLYAMINE SILICONE LIGAND SUITABLE FOR QUANTUM DOT COMPOSITIONS AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2020-07-09 US disclosed
EP-1463774-B1 NAPHTHYLTRIAZINES AS STABILIZERS FOR ORGANIC MATERIAL BASF SE (DE) 2013-07-31 EP disclosed
EP-2559735-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER Sumitomo Chemical Company Limited (JP) 2013-02-20 EP disclosed
EP-2559734-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER Sumitomo Chemical Co., Ltd (JP) 2013-02-20 EP disclosed
EP-2559736-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION Sumitomo Chemical Company Limited (JP) 2013-02-20 EP disclosed
EP-2559737-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION Sumitomo Chemical Co., Ltd (JP) 2013-02-20 EP disclosed
US-20130041086-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-14 US disclosed
US-20130032756-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 US disclosed
US-5081170-A Polyolefin, phenolic antioxidant, light stabilizer, sulfur antioxidant, talc filler, weatherproofing ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1992-01-14 US disclosed
EP-0451539-A1 Thermoplastic resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-16 EP disclosed
EP-0414916-A1 PHOSPHITE COMPOUND AND APPLICATION THEREOF YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1991-03-06 EP disclosed
US-4957953-A MONO-AND POLYTETRAMETHYLPIPERIDINE ESTERS ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-18 US disclosed
US-4956407-A POLYESTERS, POLYCARBONATES BLENDS, ACRYLONITRILE-BUTADIENE-STYRENE TERPOLYMER ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1990-09-11 US disclosed
US-4897438-A BLEND WITH A PHENOLIC RESIN HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-01-30 US disclosed
US-4888371-A HEAT RESISTANCE, LIGHT RESISTANCE ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1989-12-19 US disclosed
US-4148783-A HEAT, LIGHT, OXIDATION, AGING RESISTANCE, STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1979-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041086-A1 THERMOPLASTIC POLYMER COMPOSITION AND STABILISER COMPOSITION TAF9, INTS9, PGM2 ALDH1A1 3989/4885KMT2A 1362/4885TSHR 4846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.