Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839589 | 0.99 | ALDH1A1 (0.47) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL9838852 | 0.81 | NFE2L2 (0.37) | KMT2ASMN1; SMN2L3MBTL1SLC6A3EPHX1 | |
| SCHEMBL9838945 | 0.80 | NFE2L2 (0.39) | SMN1; SMN2L3MBTL1SLC6A3EPHX1GAA | |
| SCHEMBL10379541 | 0.80 | GAA (0.52) | ALDH1A1KMT2ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL10379312 | 0.79 | GAA (0.51) | ALDH1A1KMT2ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL10378482 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL10379783 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8020427 | 0.74 | AKR1C3 (0.49) | ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL10379521 | 0.74 | GAA (0.54) | ALDH1A1KMT2AMAPTL3MBTL1GAA | |
| SCHEMBL9837515 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276122-B1 | CYCLOALKYL-SUBSTITUTED 4-AMINOPHENYL HALO DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1991-08-07 | — | — | EP | disclosed |
| US-4847295-A | ANTITUMOR AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-07-11 | — | — | US | disclosed |
| EP-0276122-A2 | Cycloalkyl-substituted 4-aminophenyl halo derivatives and process for their preparation | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-07-27 | — | — | EP | disclosed |