Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | NQO1 | P15559 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133510 | 0.90 | CYP2D6 (0.47) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL4642360 | 0.75 | HTR2A (0.52) | CYP2D6LMNAADRA2AHTR2AALDH1A1 | |
| SCHEMBL29854083 | 0.75 | HTR2A (0.52) | CYP2D6LMNAADRA2AHTR2AALDH1A1 | |
| SCHEMBL1205626 | 0.73 | HPRT1 (0.56) | MEN1HPGDKMT2AALDH1A1KIF11 | |
| SCHEMBL24809970 | 0.73 | ALDH1A1 (0.56) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL10409091 | 0.71 | ALDH1A1 (0.54) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL981458 | 0.71 | GAA (0.40) | CYP2D6ADRA2AKIF11CYP2C19CYP1A2 | |
| SCHEMBL4562721 | 0.71 | CYP1A2 (0.41) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL28384010 | 0.70 | KIF11 (0.59) | CYP2D6LMNAMEN1HPGDKMT2A | |
| SCHEMBL5050124 | 0.70 | KIF11 (0.44) | CYP2D6NR1I2LMNAADRA2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786885-B1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | MERCK PATENT GMBH (DE) | 2011-05-18 | — | — | EP | claimed |
| US-20070252108-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | US | claimed |
| EP-2984079-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2018-11-08 | — | — | US | disclosed |
| EP-2232611-B1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9437828-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| EP-2984079-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | Power Oleds Limited (GB) | 2016-02-17 | — | — | EP | disclosed |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| EP-2318474-B1 | COMPOUND HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES AND ITS PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |
| EP-1946392-A2 | ELECTROLUMINESCENT DEVICES | OLED-T LIMITED (GB) | 2008-07-23 | — | — | EP | disclosed |
| WO-2008081178-A1 | ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008078114-A1 | ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008078115-A1 | PHENANTHROLINE COMPOUNDS AND ELECTROLUMINESCENT DEVICES USING THE SAME | MERCK PATENT GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| US-20070252108-A1 | Electroluminescent Materials and Devices | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
| EP-1786885-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | OLED-T LIMITED (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2007052083-A2 | ELECTROLUMINESCENT DEVICES | OLED-T LIMITED (GB) | 2007-05-10 | — | — | WO | disclosed |
| WO-2006090098-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | OLED-T LIMITED (GB) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006016176-A1 | ELECTROLUMINESCENT MATERIALS AND DEVICES | OLED-T LIMITED (GB) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | CYP2D6 971/4885NR1I2 465/4885LMNA 1637/4885 |
| US-20070252108-A1 | Electroluminescent Materials and Devices | AAAS, ANXA1, ANXA2 | CYP2D6 2354/4885NR1I2 3639/4885LMNA 578/4885 |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | NAT1, SLCO2A1, SLCO2B1 | CYP2D6 971/4885NR1I2 465/4885LMNA 1637/4885 |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | CYP2D6 971/4885NR1I2 465/4885LMNA 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.