Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838959 | 0.79 | KDM4E (0.35) | KDM4ENPC1MAPTATMHTT | |
| SCHEMBL9838954 | 0.79 | KDM4E (0.35) | KDM4ENPC1MAPTATMHTT | |
| SCHEMBL9837734 | 0.76 | UGT2B17 (0.34) | HSD17B10 | |
| SCHEMBL9838028 | 0.75 | KDM4E (0.50) | KDM4ENPC1MAPTATMHTT | |
| SCHEMBL16806287 | 0.74 | IGF1R (0.32) | — | |
| SCHEMBL9846190 | 0.71 | L3MBTL1 (0.46) | NPC1MAPTHTTHTR2CRAB9A | |
| SCHEMBL9838021 | 0.69 | KDM4E (0.60) | KDM4EHTTALDH1A1HPGDHSD17B10 | |
| SCHEMBL6342720 | 0.69 | PKM (0.34) | — | |
| SCHEMBL5318526 | 0.68 | ALDH1A1 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL2674287 | 0.67 | CYP1A2 (0.44) | MAPTHTTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124992-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-05-29 | — | — | EP | disclosed |
| US-4680400-A | Herbicidal cyclohexane-1,3-dione-5-isoquinoline derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-07-14 | — | — | US | disclosed |
| US-4640708-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-02-03 | — | — | US | disclosed |
| EP-0124992-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |