Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326261 | 0.83 | MAPT (0.40) | HPGDTRPV1MEN1MAPTKMT2A | |
| SCHEMBL9325277 | 0.82 | EPHX2 (0.53) | HPGDTRPV1CNR2FAAH | |
| SCHEMBL11367962 | 0.75 | HPGD (0.82) | HPGDCASP2NAAAPYGLTRPV1 | |
| SCHEMBL13287459 | 0.72 | HPGD (0.97) | HPGDTRPV1 | |
| SCHEMBL5933901 | 0.72 | HPGD (0.97) | HPGDTRPV1 | |
| SCHEMBL7888252 | 0.71 | HPGD (0.73) | HPGDCASP2NAAAPYGLTRPV1 | |
| SCHEMBL7201453 | 0.71 | HPGD (0.73) | HPGDCASP2NAAAPYGLTRPV1 | |
| SCHEMBL7197012 | 0.71 | HPGD (0.73) | HPGDCASP2NAAAPYGLTRPV1 | |
| SCHEMBL8387272 | 0.71 | HPGD (0.73) | HPGDCASP2NAAAPYGLTRPV1 | |
| SCHEMBL9345367 | 0.70 | TRPV1 (0.80) | HPGDTRPV1HSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059611-A | Treating psoriasis and modifying calcium homeostatis | ALLERGAN, INC. (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0369812-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |