SCHEMBL9839375

SCHEMBL9839375

CN1C(C)(C)CC(c2ccccc2C(=O)O)CC1(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.41
ALDH1A1 P00352 3/20 0.39
ALOX15 P16050 2/20 0.39
KDM4E B2RXH2 4/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
GAA P10253 2/20 0.36
METAP2 P50579 1/20 0.36
MYC P01106 2/20 0.36
NR4A1 P22736 1/20 0.36
MLYCD O95822 1/20 0.36
CPB1 P15086 1/20 0.35
MAPK1 P28482 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
HMGB1 P09429 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL756170 0.88 CYP2C9 (0.41) CYP2C9ALDH1A1ALOX15KDM4ETDP1
SCHEMBL4977111 0.86 ADRA1A (0.45) ALDH1A1KDM4EMETAP2HPGD
SCHEMBL9242156 0.85 KMT2A (0.40) CYP2C9ALDH1A1ALOX15KDM4ETDP1
SCHEMBL28627757 0.81 CYP2D6 (0.47) CYP2C9ALDH1A1ALOX15KDM4EL3MBTL1
SCHEMBL9243424 0.80 TSHR (0.37) CYP2C9ALDH1A1ALOX15KDM4ETDP1
SCHEMBL679141 0.79 ALOX15 (0.55) CYP2C9ALDH1A1ALOX15KDM4EL3MBTL1
SCHEMBL29903216 0.79 ALOX15 (0.55) CYP2C9ALDH1A1ALOX15KDM4EL3MBTL1
Adipic Acid SCHEMBL7642949 0.79 EGFR (0.38) CYP2C9ALDH1A1ALOX15KDM4ECYP3A4
SCHEMBL5606642 0.79 CYP1A2 (0.34) CYP2C9ALDH1A1ALOX15KDM4EL3MBTL1
SCHEMBL11164595 0.78 METAP2 (0.36) L3MBTL1METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257321-B1 IMPROVING WEATHERABILITY AND ADHERENCE OF POLYPROPYLENE ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1991-03-13 EP disclosed
US-4997888-A Tetramethyl piperidyl compound ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-03-05 US disclosed
US-4994529-A Surface activation with oxygen; piperidyl stabilizer and phenolic antioxidant present ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1991-02-19 US disclosed
EP-0257321-A2 Improving weatherability and adherence of polypropylene ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1988-03-02 EP disclosed