SCHEMBL9839376

SCHEMBL9839376

C=CC(=O)OCCSc1ccc(C(=O)C(C)(C)N2CCOCC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.58
ALDH1A1 P00352 2/20 0.58
MAPK1 P28482 2/20 0.58
TSHR P16473 1/20 0.58
HRH3 Q9Y5N1 1/20 0.44
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
FKBP1A P62942 2/20 0.36
TP53 P04637 1/20 0.36
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12724721 0.91 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL13260776 0.89 ALDH1A1 (0.43) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL12256584 0.88 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10885272 0.86 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL13291515 0.86 ALDH1A1 (0.46) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL12927094 0.86 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10890284 0.85 SMN1; SMN2 (0.67) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10885880 0.85 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL26785899 0.85 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10883782 0.85 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118020026-A Photosensitive resin composition, cured product, partition wall, organic electroluminescent element, and image display device 三菱化学株式会社 2024-05-10 CN disclosed
US-8791289-B2 Preparation method of copolymerizable photoinitiators AGFA GRAPHICS NV (BE) 2014-07-29 US disclosed
US-8791289-B2 Preparation method of copolymerizable photoinitiators AGFA GRAPHICS NV (BE) 2014-07-29 US disclosed
US-8664431-B2 Preparation method of copolymerizable photoinitiators AGFA GRAPHICS NV (BE) 2014-03-04 US disclosed
US-8664431-B2 Preparation method of copolymerizable photoinitiators AGFA GRAPHICS NV (BE) 2014-03-04 US disclosed
US-20140024840-A1 PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS AGFA GRAPHICS NV (BE) 2014-01-23 US disclosed
US-20140024840-A1 PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS AGFA GRAPHICS NV (BE) 2014-01-23 US disclosed
US-8414982-B2 Process for the production of strongly adherent coatings BASF SE (DE) 2013-04-09 US disclosed
US-20100305336-A1 PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS AGFA GRAPHICS NV (BE) 2010-12-02 US disclosed
US-20100305336-A1 PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS AGFA GRAPHICS NV (BE) 2010-12-02 US disclosed
EP-1842601-A1 Method for forming functional layers Ciba Specialty Chemicals Holding Inc. (CH) 2007-10-10 EP disclosed
WO-2007060125-A1 REACTIVE SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-05-31 WO disclosed
WO-1991003002-A1 PHOTO-CROSSLINKED POLYMERS FOR NON-LINEAR OPTICS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-07 WO disclosed
US-4582862-A QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS CIBA-GEIGY CORPORATION (US) 1986-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305336-A1 PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS HBB, HBZ, HBG1 SMN1; SMN2 4518/4885ALDH1A1 390/4885MAPK1 3096/4885
US-20140024840-A1 PREPARATION METHOD OF COPOLYMERIZABLE PHOTOINITIATORS HBB, HBZ, HBG1 SMN1; SMN2 4382/4885ALDH1A1 371/4885MAPK1 2816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.