Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368035 | 0.91 | HTT (0.56) | HTTLMNANPSR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL8612119 | 0.91 | LTA4H (0.53) | HTTLMNANPSR1SMN1; SMN2SIGMAR1 | |
| SCHEMBL9837849 | 0.89 | LMNA (0.55) | HTTLMNANPSR1SMN1; SMN2KMT2A | |
| SCHEMBL8480984 | 0.88 | LMNA (0.44) | HTTLMNANPSR1SMN1; SMN2IDO1 | |
| SCHEMBL7710668 | 0.82 | AOC3 (0.57) | HTTLMNANPSR1IDO1AOC3 | |
| SCHEMBL26695481 | 0.81 | IDO1 (0.54) | HTTSMN1; SMN2IDO1CALM1CA12 | |
| SCHEMBL11132376 | 0.79 | IDO1 (0.50) | HTTSMN1; SMN2IDO1AOC3CALM1 | |
| SCHEMBL6865347 | 0.79 | LMNA (0.49) | HTTLMNANPSR1SMN1; SMN2AOC3 | |
| SCHEMBL14679275 | 0.79 | IDO1 (0.50) | SMN1; SMN2IDO1CALM1CA12CA1 | |
| SCHEMBL6935441 | 0.79 | LMNA (0.49) | HTTLMNANPSR1SMN1; SMN2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |