Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612119 | 0.98 | LTA4H (0.53) | LMNAHTTSMN1; SMN2LTA4HKIF11 | |
| SCHEMBL10368035 | 0.95 | HTT (0.56) | LMNAHTTSMN1; SMN2LTA4HKIF11 | |
| SCHEMBL9839441 | 0.89 | HTT (0.54) | LMNAHTTSMN1; SMN2LTA4HKMT2A | |
| SCHEMBL27098301 | 0.86 | KIF11 (0.58) | LMNAHTTSMN1; SMN2LTA4HKIF11 | |
| SCHEMBL7025430 | 0.84 | LTA4H (0.53) | LMNAHTTSMN1; SMN2LTA4HKIF11 | |
| SCHEMBL30475391 | 0.84 | LTA4H (0.57) | LMNAHTTSMN1; SMN2LTA4HKIF11 | |
| SCHEMBL28596222 | 0.83 | SMN1; SMN2 (0.55) | LMNAHTTSMN1; SMN2LTA4HKIF11 | |
| SCHEMBL912792 | 0.83 | CYP2C9 (0.67) | LMNASMN1; SMN2KIF11CYP1A2CYP2C9 | |
| SCHEMBL28440590 | 0.82 | KIF11 (0.54) | LMNAHTTSMN1; SMN2LTA4HKIF11 | |
| SCHEMBL28076975 | 0.82 | KIF11 (0.54) | LMNAHTTSMN1; SMN2LTA4HKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |