Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | DGKZ | Q13574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25328216 | 0.78 | MAPK14 (0.37) | DPP8 | |
| SCHEMBL21831810 | 0.78 | MAPK14 (0.37) | DPP8 | |
| SCHEMBL5428037 | 0.78 | CHRM2 (0.54) | OPRD1CHRM2CHRM1CYP3A4OPRM1 | |
| SCHEMBL7428899 | 0.76 | LMNA (0.54) | OPRD1CYP1A2CYP3A4LMNAGAA | |
| SCHEMBL30554479 | 0.75 | TACR1 (0.38) | — | |
| SCHEMBL23126416 | 0.75 | TACR1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL7430355 | 0.75 | LMNA (0.53) | OPRD1CYP1A2CYP3A4HPGDLMNA | |
| Hydrochloric Acid SCHEMBL7434773 | 0.75 | LMNA (0.53) | OPRD1CYP1A2CYP3A4HPGDLMNA | |
| Hydrochloric Acid SCHEMBL7434945 | 0.75 | LMNA (0.53) | OPRD1CYP1A2CYP3A4HPGDLMNA | |
| SCHEMBL26925700 | 0.73 | OPRD1 (0.43) | OPRD1CYP1A2CYP3A4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028610-A | Calcium Channel Blockers | SANKYO COMPANY LIMITED (JP) | 1991-07-02 | — | — | US | disclosed |