Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030887 | 0.81 | LMNA (0.46) | ALDH1A1LMNAPOLBKMT2AGAA | |
| SCHEMBL7343985 | 0.80 | TNF (0.43) | ALDH1A1LMNANPSR1POLBKMT2A | |
| SCHEMBL9838175 | 0.80 | LMNA (0.40) | ALDH1A1LMNANPSR1POLBTNF | |
| SCHEMBL10719288 | 0.75 | TDP1 (0.46) | ALDH1A1LMNAPOLBTNFPDE4A | |
| SCHEMBL16694802 | 0.73 | TSHR (0.36) | ALDH1A1TSHRKMT2A | |
| SCHEMBL9831506 | 0.73 | TDP1 (0.41) | ALDH1A1LMNAPOLBTNFGAA | |
| SCHEMBL9860126 | 0.71 | TDP1 (0.46) | ALDH1A1LMNAPOLBKMT2ATNF | |
| SCHEMBL17916040 | 0.71 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRNPSR1POLB | |
| SCHEMBL761532 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AGAAKDM4EHPGD | |
| SCHEMBL29760385 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AGAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985328-A | Metal Complex Charge Control Agents | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0360617-A2 | Dry toner, dry developer and process for forming images | Hitachi Chemical Co., Ltd. (JP) | 1990-03-28 | — | — | EP | disclosed |