Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749961 | 0.86 | EGFR (0.44) | EGFRERBB2CNR2POLBKMT2A | |
| SCHEMBL9839720 | 0.81 | EGFR (0.39) | EGFRERBB2L3MBTL1CNR2MAPT | |
| SCHEMBL11482209 | 0.79 | EGFR (0.54) | EGFRERBB2L3MBTL1CNR2MAPT | |
| SCHEMBL627242 | 0.75 | CYP2C19 (0.45) | EGFRERBB2CNR2MAPTPOLB | |
| SCHEMBL9750091 | 0.74 | ALDH1A1 (0.50) | MAPTPOLBGAAMEN1KMT2A | |
| SCHEMBL11314840 | 0.74 | EGFR (0.58) | EGFRERBB2L3MBTL1CNR2MAPT | |
| Lithium Ion SCHEMBL19732617 | 0.73 | CYP2C19 (0.44) | EGFRERBB2CNR2POLBGAA | |
| SCHEMBL21065748 | 0.73 | CYP2C19 (0.44) | EGFRERBB2CNR2POLBGAA | |
| SCHEMBL10473319 | 0.73 | EGFR (0.47) | EGFRERBB2L3MBTL1CNR2POLB | |
| SCHEMBL1827424 | 0.72 | EGFR (0.59) | EGFRERBB2CNR2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |