Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750077 | 0.90 | MAPT (0.53) | ALDH1A1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL4897408 | 0.87 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTHDAC1HDAC6 | |
| SCHEMBL9839509 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTHDAC1HDAC6 | |
| SCHEMBL9750173 | 0.81 | MAPT (0.46) | ALDH1A1MAPTRAB9ANPC1MAPK1 | |
| Dibenzoylmethane SCHEMBL9838231 | 0.81 | RAB9A (0.56) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL14099863 | 0.80 | RAB9A (0.58) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| Malonic Acid Diethyl Ester SCHEMBL9840328 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDMAPTHDAC1RAB9A | |
| SCHEMBL9840309 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTHDAC1HDAC6 | |
| SCHEMBL11427804 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPTHDAC1HDAC6 | |
| SCHEMBL3843346 | 0.76 | MAPT (0.43) | ALDH1A1HPGDMAPTHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084593-A | Cyanine, aniline dyes for heat sensitive recording elements | RICOH COMPANY, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5057154-A | Colorfastness, stability | RICOH COMPANY, LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4939117-A | Leuco dyes and recording material employing the same | RICOH COMPANY, LTD. (JP) | 1990-07-03 | — | — | US | disclosed |