Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749957 | 0.88 | HDAC3 (0.40) | EGFRERBB2CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL9839723 | 0.81 | EGFR (0.47) | EGFRERBB2CNR2L3MBTL1ESRRG | |
| SCHEMBL9750086 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTHDAC3HDAC1 | |
| SCHEMBL9839524 | 0.77 | CNR2 (0.45) | EGFRERBB2CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL9839734 | 0.76 | EGFR (0.44) | EGFRERBB2CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL9838463 | 0.73 | EGFR (0.46) | EGFRERBB2CNR2ESRRGALDH1A1 | |
| SCHEMBL11482209 | 0.73 | EGFR (0.54) | EGFRERBB2CNR2L3MBTL1ALDH1A1 | |
| SCHEMBL9750072 | 0.71 | MAPT (0.47) | L3MBTL1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL627242 | 0.70 | CYP2C19 (0.45) | EGFRERBB2CNR2ALDH1A1KDM4E | |
| SCHEMBL9840321 | 0.69 | CNR2 (0.43) | EGFRERBB2CNR2L3MBTL1ESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5008238-A | Thermosensitive material with phenolic developer | RICOH COMPANY, LTD. (JP) | 1991-04-16 | — | — | US | disclosed |