SCHEMBL9839737

SCHEMBL9839737

Cc1cc(CCc2cc(C)c(C)c(C)c2C)c(C)c(C)c1C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
ALOX15 P16050 1/20 0.33
CASP7 P55210 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27719431 0.87 ALDH1A1 (0.33) NPSR1ALDH1A1CYP1A2ALOX15CASP7
SCHEMBL1611661 0.85 NPSR1 (0.31) NPSR1
SCHEMBL27439700 0.85 ALDH1A1 (0.33) NPSR1ALDH1A1CYP1A2ALOX15CASP7
SCHEMBL1287616 0.83 TYR (0.39) NPSR1ALDH1A1ALOX15
SCHEMBL26135708 0.82 MAOA (0.39) ALDH1A1ALOX15HSD17B10TAAR1
SCHEMBL13324501 0.82 ALDH1A1 (0.44) NPSR1ALDH1A1CYP1A2ALOX15CASP7
SCHEMBL28346676 0.81 NOS3 (0.35)
SCHEMBL1611469 0.81
SCHEMBL1087300 0.80 NOS3 (0.37) NPSR1ALDH1A1CYP1A2ALOX15CASP7
SCHEMBL5349748 0.80 ALDH1A1 (0.32) NPSR1ALDH1A1CYP1A2ALOX15CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0290050-B1 METHOD FOR PRODUCING ALKYLSTYRENE NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-08-21 EP disclosed
US-5026939-A Cracking 1,2-di(4-isobutylphenyl)ethane in contact with acid catalyst NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-06-25 US disclosed
EP-0290050-A1 Method for producing alkylstyrene NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed