Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 15/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 15/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 15/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 14/20 | 0.37 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.33 |
| ▸ | GABRP | O00591 | 4/20 | 0.33 |
| ▸ | GABRD | O14764 | 4/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.33 |
| ▸ | GABRE | P78334 | 4/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839924 | 0.90 | PIKFYVE (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9839098 | 0.88 | GABRA1 (0.37) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10376400 | 0.84 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9840097 | 0.82 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10732732 | 0.82 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9840565 | 0.82 | PIKFYVE (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9838966 | 0.79 | GABRA1 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9839911 | 0.78 | GABRA1 (0.33) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9840061 | 0.78 | GABRP (0.31) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9840036 | 0.78 | GABRA1 (0.32) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222693-B1 | 3-OXADIAZOLYL AND 3-CARBOXYLIC-ACID BETA-CARBOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-17 | — | — | EP | disclosed |
| US-4778800-A | ANXIOLYTIC, ANTICONVULSANT | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |