Fluoride

Fluoride

SCHEMBL9839839

CCCCCCCCCCCCCCN(C)C.F

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 7/20 0.94
TSHR P16473 2/20 0.69
ALDH1A1 P00352 1/20 0.69
THRB P10828 1/20 0.50
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
S1PR2 O95136 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
S1PR5 Q9H228 1/20 0.41
SIGMAR1 Q99720 2/20 0.39
GBA1 P04062 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL25238730 1.00 DNM1 (0.94) DNM1TSHRALDH1A1THRBCA12
Fluoride SCHEMBL27688543 1.00 DNM1 (0.94) DNM1TSHRALDH1A1THRBCA12
Fluoride SCHEMBL20497333 1.00 DNM1 (0.94) DNM1TSHRALDH1A1THRBCA12
Fluoride SCHEMBL9450603 1.00 DNM1 (0.94) DNM1TSHRALDH1A1THRBCA12
Fluoride SCHEMBL17743529 1.00 DNM1 (0.94) DNM1TSHRALDH1A1THRBCA12
SCHEMBL284680 0.97 DNM1 (1.00) DNM1TSHRALDH1A1THRBCA12
SCHEMBL1730438 0.97 DNM1 (1.00) DNM1TSHRALDH1A1THRBCA12
SCHEMBL119304 0.97 DNM1 (1.00) DNM1TSHRALDH1A1THRBCA12
Dymanthine SCHEMBL61784 0.97 DNM1 (1.00) DNM1TSHRALDH1A1THRBCA12
SCHEMBL9807721 0.97 DNM1 (1.00) DNM1TSHRALDH1A1THRBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3972698-B1 ORAL COMPOSITIONS AND METHODS OF USE SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-02-12 EP disclosed
EP-3463584-B1 THERAPEUTIC DENTAL PASTES AND THE APPLICATION THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-27 EP disclosed
US-20230293393-A1 NATURAL TOOTH POWDER TABLETS MCCORMICK LINDSAY (US) 2023-09-21 US disclosed
US-11701306-B2 Natural tooth powder tablets MCCORMICK LINDSAY (US) 2023-07-18 US disclosed
US-11696879-B2 Therapeutic dental pastes and related methods and kits 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-11 US disclosed
US-20220211603-A1 Oral Compositions And Methods Of Use SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2022-07-07 US disclosed
US-20220192953-A1 Oral Compositions And Methods Of Use 3M INNOVATIVE PROPERTIES COMPANY 2022-06-23 US disclosed
EP-3972557-A1 ORAL COMPOSITIONS AND METHODS OF USE 3M Innovative Properties Company (US) 2022-03-30 EP disclosed
EP-3972698-A1 ORAL COMPOSITIONS AND METHODS OF USE 3M Innovative Properties Company (US) 2022-03-30 EP disclosed
EP-0297212-B1 ORAL COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1991-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696879-B2 Therapeutic dental pastes and related methods and kits PROC, DNASE1, COL2A1 DNM1 2086/4885TSHR 4358/4885ALDH1A1 1617/4885
US-20220211603-A1 Oral Compositions And Methods Of Use MSR1, GCK, TAS2R40 DNM1 3302/4885TSHR 838/4885ALDH1A1 4423/4885
US-20220192953-A1 Oral Compositions And Methods Of Use HRH2, HRH3, HRH4 DNM1 988/4885TSHR 1559/4885ALDH1A1 4776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.