SCHEMBL9840091

SCHEMBL9840091

CCCC(N)c1ccccc1C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
KMT2A Q03164 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
GAA P10253 1/20 0.44
ALOX15 P16050 1/20 0.43
KDM4E B2RXH2 3/20 0.43
MEN1 O00255 1/20 0.43
RECQL P46063 1/20 0.43
MAPT P10636 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
POLB P06746 2/20 0.41
TSHR P16473 1/20 0.41
CA12 O43570 3/20 0.40
CA9 Q16790 3/20 0.40
MYC P01106 1/20 0.39
HPGD P15428 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
HMGB1 P09429 1/20 0.38
CA4 P22748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28872236 0.86 LMNA (0.38) ALDH1A1TDP1KDM4EMAPTTSHR
SCHEMBL9839451 0.86 ALDH1A1 (0.46) ALDH1A1KMT2ATDP1GAAALOX15
SCHEMBL7617935 0.82 ALDH1A1 (0.46) ALDH1A1KMT2ATDP1GAAALOX15
SCHEMBL21436062 0.82 ALDH1A1 (0.49) ALDH1A1KMT2AGAAALOX15KDM4E
SCHEMBL28259253 0.81 ALDH1A1 (0.50) ALDH1A1KMT2ATDP1GAAALOX15
SCHEMBL6859419 0.81 KMT2A (0.47) ALDH1A1KMT2ATDP1GAAALOX15
SCHEMBL1439982 0.79 ALDH1A1 (0.44) ALDH1A1KMT2ATDP1GAAALOX15
SCHEMBL6876901 0.79 POLB (0.44) ALDH1A1KMT2ATDP1GAAALOX15
SCHEMBL16824139 0.79 ALDH1A1 (0.47) ALDH1A1KMT2ATDP1GAAALOX15
SCHEMBL14660916 0.79 ALDH1A1 (0.44) ALDH1A1KMT2ATDP1GAAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN claimed
CN-107108638-A Piperidyl PyrazolopyrimidinonecGMP and application thereof 拜耳制药股份公司 2017-08-29 CN claimed
CN-105683194-A (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones as inhibitors of fibrinolysis 拜耳制药股份公司 2016-06-15 CN claimed
EP-0254009-B1 A PROCESS FOR PURIFYING DINITROANILINE HERBICIDES AGAN CHEMICAL MANUFACTURERS LTD. (IL) 1991-04-17 EP claimed
CN-109415553-A The thermosetting resin of plasticising and related solidified resin, curing method and the product comprising solidified resin 马萨诸塞大学 2019-03-01 CN disclosed
CN-105683194-B The inhibitor of (azepine) pyrido PyrazolopyrimidinonecGMP and indazole hepyramine as fibrinolysis 拜耳制药股份公司 2018-09-14 CN disclosed
CN-107108638-A Piperidyl PyrazolopyrimidinonecGMP and application thereof 拜耳制药股份公司 2017-08-29 CN disclosed
CN-105683194-A (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones as inhibitors of fibrinolysis 拜耳制药股份公司 2016-06-15 CN disclosed
CN-103127402-A Application of swallow cimitin in preparation of whitening and freckle removing product YANG YANJIAO 2013-06-05 CN disclosed