Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1548478 | 0.93 | TSHR (0.51) | THRBTSHRGAAPOLBAPEX1 | |
| SCHEMBL8769599 | 0.92 | GAA (0.41) | THRBTSHRGAAALDH1A1CYP4F2 | |
| SCHEMBL2505517 | 0.90 | THRB (0.52) | THRBTSHRPOLBAPEX1HTT | |
| 1,4-Butanediol SCHEMBL16265704 | 0.90 | THRB (0.66) | THRBTSHRGAAPOLBAPEX1 | |
| 1,6-Hexanediol SCHEMBL17420126 | 0.88 | THRB (0.63) | THRBTSHRGAAPOLBAPEX1 | |
| 1,6-Hexanediol SCHEMBL9436385 | 0.88 | THRB (0.63) | THRBTSHRGAAPOLBAPEX1 | |
| SCHEMBL13397682 | 0.86 | THRB (0.61) | THRBTSHRGAAPOLBAPEX1 | |
| 1,4-Butanediol SCHEMBL14911112 | 0.86 | THRB (0.61) | THRBTSHRGAAPOLBAPEX1 | |
| SCHEMBL8850641 | 0.86 | THRB (0.61) | THRBTSHRGAAPOLBAPEX1 | |
| SCHEMBL8145264 | 0.86 | THRB (0.41) | THRBTSHRGAAALDH1A1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003310-A1 | PROCESS FOR SURFACE-GRAFTING OF FORMED MATERIALS, IN PARTICULAR ALSO MICROPOROUS MEMBRANES MADE FROM NITROGEN CONTAINING POLYMERS | SARTORIUS AG (DE) | 1991-03-21 | — | — | WO | claimed |