SCHEMBL9840348

SCHEMBL9840348

[CH2]c1ccc(C(F)(F)C(F)F)nc1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130933 0.79 TRPV4 (0.58) TRPV4
SCHEMBL9838963 0.79 TRPV4 (0.41) TRPV4
SCHEMBL10564658 0.75 TRPV4 (0.39) TRPV4
SCHEMBL9838974 0.75 TRPV4 (0.39) TRPV4
SCHEMBL27856899 0.75 TRPV4 (0.39) TRPV4
SCHEMBL131736 0.72 MLYCD (0.43) TRPV4
SCHEMBL15122279 0.70 TRPV4 (0.32) TRPV4
SCHEMBL9840065 0.69
SCHEMBL10511820 0.67
SCHEMBL133858 0.67 TGFBR1 (0.34) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212600-B1 NITROMETHYLENE DERIVATIVES NIHON BAYER AGROCHEM K.K. (JP) 1991-11-27 EP disclosed
US-4812454-A Nitromethylene derivatives and their use as insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-03-14 US disclosed
US-4772620-A MITICIDES, PARASITICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-09-20 US disclosed
EP-0212600-A2 Nitromethylene derivatives NIHON BAYER AGROCHEM K.K. (JP) 1987-03-04 EP disclosed