Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | LTA | P01374 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | RAD1 | O60671 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332762 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2P2RY6ALDH1A1CYP3A4 | |
| SCHEMBL18245391 | 0.85 | GABRA1 (0.50) | GABRA1GABRB2P2RY6ALDH1A1CYP3A4 | |
| SCHEMBL6961977 | 0.80 | GABRA1 (0.50) | GABRA1GABRB2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL29376372 | 0.79 | CYP3A4 (0.61) | GABRA1GABRB2ALDH1A1CYP3A4HPGD | |
| SCHEMBL314237 | 0.79 | CYP3A4 (0.61) | GABRA1GABRB2ALDH1A1CYP3A4HPGD | |
| SCHEMBL4739068 | 0.76 | P2RY6 (0.46) | P2RY6ALDH1A1CYP3A4HSD17B10MAPT | |
| SCHEMBL484205 | 0.75 | CYP3A4 (0.60) | P2RY6ALDH1A1CYP3A4HSD17B10MAPT | |
| SCHEMBL29463953 | 0.75 | CYP3A4 (0.60) | P2RY6ALDH1A1CYP3A4HSD17B10MAPT | |
| SCHEMBL945820 | 0.75 | GABRA1 (0.62) | GABRA1GABRB2ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL18245194 | 0.74 | P2RY6 (0.47) | GABRA1GABRB2P2RY6ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011861-A | Containing functional groups capable of bonding peptides and proteins | MILLIPORE CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0353460-A2 | Membranes for solid phase protein sequencing | MILLIPORE CORPORATION (US) | 1990-02-07 | — | — | EP | disclosed |