Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840461 | 1.00 | RAB9A (0.43) | RAB9AMAPTNPC1SMN1; SMN2ATM | |
| SCHEMBL9630649 | 0.89 | RAB9A (0.49) | RAB9AMAPTNPC1SMN1; SMN2ATM | |
| SCHEMBL9630624 | 0.89 | RAB9A (0.49) | RAB9AMAPTNPC1SMN1; SMN2ATM | |
| SCHEMBL9840404 | 0.84 | L3MBTL1 (0.48) | RAB9AMAPTNPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9628701 | 0.82 | RARB (0.43) | RAB9AMAPTNPC1SMN1; SMN2ATM | |
| SCHEMBL9237482 | 0.80 | KDM4E (0.41) | RAB9AMAPTNPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9617654 | 0.79 | RAB9A (0.53) | RAB9AMAPTNPC1SMN1; SMN2ATM | |
| SCHEMBL9239432 | 0.79 | L3MBTL1 (0.43) | RAB9AMAPTNPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10749923 | 0.79 | RAB9A (0.45) | RAB9AMAPTNPC1SMN1; SMN2ATM | |
| SCHEMBL9239883 | 0.79 | RAB9A (0.45) | RAB9AMAPTNPC1SMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | claimed |
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |