Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16982221 | 0.84 | TDP1 (0.42) | PKMTDP1MAPTHPGDTP53 | |
| SCHEMBL11942200 | 0.81 | FKBP1A (0.47) | DRD4TDP1MAPTFKBP1AL3MBTL1 | |
| SCHEMBL7890171 | 0.81 | TDP1 (0.45) | PKMTDP1MAPTL3MBTL1HPGD | |
| SCHEMBL4764762 | 0.81 | APP (0.44) | PKMTDP1MAPTHPGDTP53 | |
| SCHEMBL11937238 | 0.80 | TP53 (0.54) | MAPTPOLBL3MBTL1HPGDTP53 | |
| SCHEMBL11284846 | 0.80 | TDP1 (0.62) | DRD4TDP1TP53TSHRMEN1 | |
| SCHEMBL6099389 | 0.78 | PKM (0.76) | PKMDRD4TDP1MAPTCA12 | |
| SCHEMBL410250 | 0.78 | PKM (0.76) | PKMDRD4TDP1MAPTCA12 | |
| SCHEMBL5994567 | 0.78 | PKM (0.76) | PKMDRD4TDP1MAPTCA12 | |
| SCHEMBL9781216 | 0.78 | MAOB (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002515-A1 | ANTI-INFLAMMATORY SUBSTANCES FOR COSMETIC PREPARATION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-03-07 | — | — | WO | disclosed |