SCHEMBL4764762

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16982221	0.84	TDP1 (0.42)	TDP1TP53MAPTHPGDTSHR
	SCHEMBL7890171	0.81	TDP1 (0.45)	APPTDP1TP53MAPTHPGD
	SCHEMBL9840578	0.81	PKM (0.51)	TDP1TP53MAPTHPGDTSHR
	SCHEMBL11284846	0.80	TDP1 (0.62)	TDP1TP53TSHRALDH1A1MEN1
	SCHEMBL7965384	0.78	TDP1 (0.66)	APPTDP1TP53MAPTHPGD
	SCHEMBL7965385	0.78	TDP1 (0.66)	APPTDP1TP53MAPTHPGD
	SCHEMBL1228641	0.78	TDP1 (0.66)	APPTDP1TP53MAPTHPGD
	SCHEMBL11942200	0.78	FKBP1A (0.47)	TDP1TP53MAPTHPGDTSHR
	SCHEMBL9781216	0.78	MAOB (0.43)	TDP1
	SCHEMBL9778566	0.78	FFAR4 (0.50)	TDP1ALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.