Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840681 | 0.83 | KDM4E (0.38) | MAPTKDM4EGLAADORA1ALDH1A1 | |
| SCHEMBL9015109 | 0.69 | ALDH1A1 (0.41) | MAPTKDM4EGLAADORA1ALDH1A1 | |
| SCHEMBL2164878 | 0.69 | DRD1 (0.34) | MAPTALDH1A1SMN1; SMN2KMT2AHTT | |
| SCHEMBL9840597 | 0.66 | KDM4E (0.46) | MAPTKDM4EGLAADORA1ALDH1A1 | |
| SCHEMBL9015062 | 0.66 | KDM4E (0.48) | MAPTKDM4EGLAALDH1A1SMN1; SMN2 | |
| SCHEMBL7980645 | 0.65 | CYP1A2 (0.46) | MAPTGAA | |
| SCHEMBL9446496 | 0.65 | IDO1 (0.37) | MAPTKDM4EGLAALDH1A1KMT2A | |
| SCHEMBL10582426 | 0.62 | ALDH1A1 (0.38) | MAPTALDH1A1KMT2AGAAHTT | |
| SCHEMBL9446485 | 0.62 | GRM5 (0.47) | MAPTKDM4EGLAADORA1ALDH1A1 | |
| SCHEMBL9339832 | 0.61 | PDE9A (0.48) | MAPTKDM4EGLAADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |