Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9339832 | 0.79 | PDE9A (0.48) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL27425531 | 0.71 | GAA (0.45) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL28035241 | 0.70 | CHUK (0.42) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL9337593 | 0.68 | PIM1 (0.35) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL9840681 | 0.67 | KDM4E (0.38) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL9840879 | 0.66 | ABCC8 (0.33) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL9840686 | 0.66 | MAPT (0.35) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL9015062 | 0.66 | KDM4E (0.48) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL15996359 | 0.64 | POLB (0.50) | KDM4EGAAKMT2AALDH1A1MAPT | |
| SCHEMBL9224576 | 0.64 | ALDH1A1 (0.49) | KDM4EGAAKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |