Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | GLA | P06280 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NRP1 | O14786 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015109 | 0.85 | ALDH1A1 (0.41) | KDM4EGLAMAPTTRPV1ADORA1 | |
| SCHEMBL9840686 | 0.83 | MAPT (0.35) | KDM4EGLAMAPTADORA1ALDH1A1 | |
| SCHEMBL9446496 | 0.80 | IDO1 (0.37) | KDM4EGLAMAPTTRPV1ALDH1A1 | |
| SCHEMBL1907911 | 0.68 | ALDH1A1 (0.48) | KDM4EMAPTTRPV1ALDH1A1HTT | |
| SCHEMBL9840597 | 0.67 | KDM4E (0.46) | KDM4EGLAMAPTADORA1ALDH1A1 | |
| SCHEMBL9015062 | 0.67 | KDM4E (0.48) | KDM4EGLAMAPTALDH1A1GAA | |
| SCHEMBL9393467 | 0.66 | KDM4E (0.34) | KDM4EGLAMAPTPIM1DHODH | |
| SCHEMBL9389298 | 0.65 | KDM4E (0.34) | KDM4EGLAMAPTADORA1ALDH1A1 | |
| SCHEMBL7980644 | 0.64 | KIF11 (0.45) | TRPV1ALDH1A1GAA | |
| SCHEMBL9840859 | 0.63 | TRPV1 (0.32) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |