SCHEMBL442211

SCHEMBL442211

CC#Cc1cn([C@H]2CC(O)[C@@H](CO)O2)c(=O)nc1N

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 6/20 0.57
ADRB1 P08588 1/20 0.57
DNMT3B Q9UBC3 2/20 0.50
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PNP P00491 1/20 0.45
TP53 P04637 1/20 0.45
HTT P42858 1/20 0.45
PDE4D Q08499 1/20 0.45
PDE3A Q14432 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
FPR2 P25090 1/20 0.45
TK1 P04183 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5983084 1.00 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5983092 1.00 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL149389 1.00 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL25492471 1.00 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL23523712 0.96 DNMT1 (0.53) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL27171596 0.89 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL7222104 0.88 DNMT1 (0.56) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL9840726 0.88 DNMT1 (0.56) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL8755221 0.88 DNMT1 (0.56) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL7222108 0.88 DNMT1 (0.56) DNMT1ADRB1DNMT3BLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 965 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO claimed
US-20090307805-A1 ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE KEYGENE N.V 2009-12-10 US claimed
US-6355785-B1 ENZYME INHIBITORS ARONEX PHARMACEUTICALS, INC. 2002-03-12 US claimed
WO-2000028087-A1 A LIBRARY OF MODIFIED PRIMERS FOR NUCLEIC ACID SEQUENCING, AND METHOD OF USE THEREOF SEQUETECH CORPORATION (US) 2000-05-18 WO claimed
US-5633360-A CONTAINS AT LEAST TWO NUCLEOSIDE RESIDUES AND INTERNUCLEOTIDE LINKAGES GILEAD SCIENCES, INC. (US) 1997-05-27 US claimed
EP-0573479-A1 CHIMERIC TAR ENZYME CONSTRUCTION FOR HIV THERAPY THE WELLCOME FOUNDATION LIMITED (GB) 1993-12-15 EP claimed
WO-1992015693-A1 CHIMERIC TAR ENZYME CONSTRUCTION FOR HIV THERAPY THE WELLCOME FOUNDATION LIMITED (GB) 1992-09-17 WO claimed
US-5079235-A 5-Substituted Pyrimidine Nucleosides BURROUGHS WELLCOME CO. (US) 1992-01-07 US claimed
EP-0272065-A2 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-06-22 EP claimed
US-12618063-B2 Pan-genotypic agents against influenza virus and methods of using the same THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-05 US disclosed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US disclosed
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS OPENTRONS LABWORKS INC (US) 2026-03-05 US disclosed
US-12522827-B2 Pan-genotypic agents against influenza virus and methods of using the same THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-01-13 US disclosed
WO-1992015693-A1 CHIMERIC TAR ENZYME CONSTRUCTION FOR HIV THERAPY THE WELLCOME FOUNDATION LIMITED (GB) 1992-09-17 WO disclosed
EP-0486477-A2 1-( -D-Arabinofuranosyl)-5-propynyluracil as a VZV-antiviral compound THE WELLCOME FOUNDATION LIMITED (GB) 1992-05-20 EP disclosed
US-5079235-A 5-Substituted Pyrimidine Nucleosides BURROUGHS WELLCOME CO. (US) 1992-01-07 US disclosed
EP-0417560-A1 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1991-03-20 EP disclosed
EP-0272065-A2 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM DNMT1 274/4885ADRB1 4500/4885DNMT3B 332/4885
US-12618063-B2 Pan-genotypic agents against influenza virus and methods of using the same ADAR, MTAP, PNP DNMT1 2516/4885ADRB1 1851/4885DNMT3B 1911/4885
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT DNMT1 384/4885ADRB1 4067/4885DNMT3B 303/4885
US-20260066042-A1 METHODS AND SYSTEMS FOR HIGH-THROUGHPUT MOLECULAR ANALYSIS POLRMT, POLL, SARS1 DNMT1 1090/4885ADRB1 2217/4885DNMT3B 1107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.