SCHEMBL149389

SCHEMBL149389

CC#Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)nc1N

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 6/20 0.57
ADRB1 P08588 1/20 0.57
DNMT3B Q9UBC3 2/20 0.50
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PNP P00491 1/20 0.45
TP53 P04637 1/20 0.45
HTT P42858 1/20 0.45
PDE4D Q08499 1/20 0.45
PDE3A Q14432 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
FPR2 P25090 1/20 0.45
TK1 P04183 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5983084 1.00 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL5983092 1.00 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL442211 1.00 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL25492471 1.00 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL23523712 0.96 DNMT1 (0.53) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL27171596 0.89 DNMT1 (0.57) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL7222104 0.88 DNMT1 (0.56) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL9840726 0.88 DNMT1 (0.56) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL8755221 0.88 DNMT1 (0.56) DNMT1ADRB1DNMT3BLMNASMN1; SMN2
SCHEMBL7222108 0.88 DNMT1 (0.56) DNMT1ADRB1DNMT3BLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
EP-4271389-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2023-11-08 EP claimed
CN-116916936-A Compositions and methods for delivering RNA 再生技术有限责任公司 2023-10-20 CN claimed
WO-2022147039-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES INC. (US) 2022-07-07 WO claimed
EP-2643460-B1 METHODS, COMPOSITIONS, AND KITS FOR DETERMINING HUMAN IMMUNODEFICIENCY VIRUS (HIV) GRIFOLS THERAPEUTICS INC (US) 2017-07-26 EP claimed
US-20140120526-A1 METHODS, COMPOSITIONS, AND KITS FOR DETERMINING HUMAN IMMUNODEFICIENCY VIRUS (HIV) Grifols Therapeutics Inc. (US) 2014-05-01 US claimed
EP-2643460-A2 METHODS, COMPOSITIONS, AND KITS FOR DETERMINING HUMAN IMMUNODEFICIENCY VIRUS (HIV) Grifols Therapeutics Inc. (US) 2013-10-02 EP claimed
WO-2012174187-A2 METHODS, COMPOSITIONS, AND KITS FOR DETERMINING HUMAN IMMUNODEFICIENCY VIRUS (HIV) Grifols Therapeutics Inc. (US) 2012-12-20 WO claimed
US-20090307805-A1 ALTERNATIVE NUCLEOTIDES FOR IMPROVED TARGETED NUCLEOTIDE EXCHANGE KEYGENE N.V 2009-12-10 US claimed
US-6355785-B1 ENZYME INHIBITORS ARONEX PHARMACEUTICALS, INC. 2002-03-12 US claimed
US-6355418-B1 HYBRIDIZING CHIMERIC OLIGONUCLEOTIDE SEQUENCES TO MRNA, FORMING DUPLEXES; THE NUCLEOTIDE SEQUENCES CONTAINS A REGION THAT IS TARGETED BY A DUPLEX CUTTING RNASE, WHEN THERE IS HYBRIDIZATION TO THE MRNA; AS WELL AS A STABILIZING REGION XZILLION GMBH & CO. KG (DE) 2002-03-12 US claimed
WO-1999027086-A1 CHIMERIC ANTISENSE OLIGONUCLEOTIDES AGAINST TNF-ALPHA AND THEIR USES BRAX GROUP LIMITED (GB) 1999-06-03 WO claimed
EP-0857208-A2 CHIMAERIC OLIGONUCLEOTIDES AND USES THEREOF IN THE IDENTIFICATION OF ANTISENSE BINDING SITES Brax Genomics Limited (GB) 1998-08-12 EP claimed
US-5633360-A CONTAINS AT LEAST TWO NUCLEOSIDE RESIDUES AND INTERNUCLEOTIDE LINKAGES GILEAD SCIENCES, INC. (US) 1997-05-27 US claimed
WO-1997010332-A2 CHIMAERIC OLIGONUCLEOTIDES AND USES THEREOF IN THE IDENTIFICATION OF ANTISENSE BINDING SITES BRAX GENOMICS LIMITED (GB) 1997-03-20 WO claimed
EP-0573479-A1 CHIMERIC TAR ENZYME CONSTRUCTION FOR HIV THERAPY THE WELLCOME FOUNDATION LIMITED (GB) 1993-12-15 EP claimed
WO-1992015693-A1 CHIMERIC TAR ENZYME CONSTRUCTION FOR HIV THERAPY THE WELLCOME FOUNDATION LIMITED (GB) 1992-09-17 WO claimed
US-5079235-A 5-Substituted Pyrimidine Nucleosides BURROUGHS WELLCOME CO. (US) 1992-01-07 US claimed
EP-0272065-A2 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-06-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA RNASE1, POLRMT, TERT DNMT1 384/4885ADRB1 4067/4885DNMT3B 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.