Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840841 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28358893 | 0.74 | KMT2A (0.51) | KEAP1NFE2L2ALDH1A1HTTALOX12 | |
| SCHEMBL9840834 | 0.73 | ALDH1A1 (0.33) | KEAP1NFE2L2ALDH1A1HTTALOX12 | |
| SCHEMBL7194392 | 0.73 | KEAP1 (0.57) | KEAP1NFE2L2ALDH1A1HTTALOX12 | |
| SCHEMBL27040077 | 0.72 | KEAP1 (0.48) | KEAP1NFE2L2ALDH1A1HTTALOX12 | |
| SCHEMBL10528432 | 0.72 | KEAP1 (0.48) | KEAP1NFE2L2ALDH1A1HTTALOX12 | |
| SCHEMBL1642775 | 0.72 | S1PR1 (0.37) | ALDH1A1HTTMEN1KMT2APKM | |
| SCHEMBL13069611 | 0.71 | KEAP1 (0.47) | KEAP1NFE2L2ALDH1A1HTTALOX12 | |
| SCHEMBL7580913 | 0.71 | HPGD (0.32) | TSHR | |
| SCHEMBL9013754 | 0.70 | KEAP1 (0.49) | KEAP1NFE2L2ALDH1A1HTTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992559-A | Electrochromic displays, antistatic agents, pH detectors, electrodes | COOKSON GROUP PLC (GB) | 1991-02-12 | — | — | US | disclosed |
| EP-0253594-A2 | Polymerisable thiophene monomers, their production and polymers prepared therefrom | COOKSON GROUP plc (GB) | 1988-01-20 | — | — | EP | disclosed |