Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039932 | 0.75 | ADORA3 (0.33) | ADORA3ADORA2A | |
| SCHEMBL8397425 | 0.73 | HTT (0.51) | MPITDP1LMNAGAAMAPT | |
| SCHEMBL918366 | 0.73 | HTT (0.51) | MPITDP1LMNAGAAMAPT | |
| SCHEMBL4603835 | 0.69 | KMT2A (0.53) | MPITDP1LMNAGAAMAPT | |
| SCHEMBL25890244 | 0.69 | MEN1 (0.44) | LMNAADORA3ADORA2AGAAMAPT | |
| SCHEMBL25891479 | 0.68 | GAA (0.38) | LMNAADORA3ADORA2AGAAMAPT | |
| SCHEMBL5975249 | 0.68 | MPI (0.43) | MPITDP1LMNAMAPTHTT | |
| SCHEMBL3809912 | 0.68 | POLB (0.43) | MPITDP1LMNAMAPTHTT | |
| SCHEMBL4602881 | 0.68 | MPI (0.43) | MPITDP1MAPTHTTKMT2A | |
| SCHEMBL4604095 | 0.68 | MPI (0.43) | MPITDP1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4986934-A | SPIROBENZOXAZINE PYRROLOPYRIDINE COMPOUNDS, EYEGLASSES | PPG INDUSTRIES, INC. (US) | 1991-01-22 | — | — | US | disclosed |