Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 5/20 | 0.38 |
| ▸ | RNASEH1 | O60930 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5984487 | 0.73 | ACHE (0.39) | ALDH1A1MAPTPIM1KDM4EKMT2A | |
| SCHEMBL9319282 | 0.70 | MAPT (0.56) | ALDH1A1MAPTSMN1; SMN2SELLSELP | |
| SCHEMBL31070283 | 0.69 | MAPT (0.63) | ALDH1A1MAPTKDM4EKMT2AACHE | |
| SCHEMBL29966114 | 0.69 | MAPT (0.63) | ALDH1A1MAPTKDM4EKMT2AACHE | |
| SCHEMBL6881938 | 0.69 | MAPT (0.63) | ALDH1A1MAPTKDM4EKMT2AACHE | |
| SCHEMBL31279731 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL2745093 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL17866966 | 0.68 | ACHE (0.75) | ALDH1A1MAPTKMT2AACHE | |
| SCHEMBL28226188 | 0.68 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E | |
| SCHEMBL29860539 | 0.68 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2PIM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |