SCHEMBL9840971

SCHEMBL9840971

[CH2]CCOC(=O)C[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.33
ADRA1A P35348 1/20 0.33
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
NAAA Q02083 1/20 0.31
CYP2C19 P33261 1/20 0.31
DGKA P23743 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29020327 0.78 NAAA (0.41) MAPTNAAADGKA
SCHEMBL50266 0.75
SCHEMBL8979257 0.74
SCHEMBL4464073 0.72
SCHEMBL435045 0.72 GAA (0.57)
SCHEMBL4292348 0.72
SCHEMBL128904 0.71
SCHEMBL7052408 0.71
SCHEMBL94709 0.71 GAA (0.50) ADRA2AADRA1AMAPTBLMNAAA
SCHEMBL29066752 0.71 ADRA2A (0.30) ADRA2AADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5061762-A MODIFIED POLY(ORGANO-ORGANOSILOXANES) WITH COMB OR BLOCK STRUCTURES AND A PROCESS FOR THEIR PREPARATION WACKER-CHEMIE GMBH (DE) 1991-10-29 US disclosed