Sugi Predict

Sugi Predict / Compounds / SCHEMBL435045

SCHEMBL435045

SCHEMBL435045

CCOC(=O)C[Si](C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.57
▸ MGAM O43451 1/20 0.57
▸ SI P14410 1/20 0.57
▸ MGAM2 Q2M2H8 1/20 0.57
▸ ALDH1A1 P00352 4/20 0.52
▸ TRPA1 O75762 1/20 0.52
▸ LMNA P02545 2/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ CYP1A2 P05177 1/20 0.44
▸ ALOX15 P16050 1/20 0.43
▸ SOAT1 P35610 1/20 0.43
▸ CA12 O43570 2/20 0.40
▸ CA1 P00915 2/20 0.40
▸ CA2 P00918 2/20 0.40
▸ CA9 Q16790 2/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ NR1I2 O75469 1/20 0.39
▸ PGR P06401 1/20 0.39
▸ ADORA3 P0DMS8 1/20 0.39
▸ PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL631915 0.83 GAA (0.57) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL15091820 0.81 GAA (0.55) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL9317153 0.80 ALDH1A1 (0.39) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL9478472 0.79 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL19770562 0.79 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL29020327 0.79 NAAA (0.41) ALDH1A1LMNAMAPK1TSHR
SCHEMBL19770545 0.79 GAA (0.52) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL5362609 0.79 CYP1A2 (0.42) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3917867 0.77 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL2885818 0.77 GAA (0.50) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 482 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428490-B2 Methods and compositions for chimeric antigen receptor targeting cancer cells THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2025-09-30 — — US claimed
CN-120136069-A Dispersible mesoporous carbon sphere and preparation method thereof 中国科学院青岛生物能源与过程研究所 2025-06-13 — — CN claimed
CN-119919663-A Weak supervision semantic segmentation method and system based on text mask collaboration prompt 广东技术师范大学 2025-05-02 — — CN claimed
WO-2025049220-A1 ELECTROLYTE COMPRISING IMIDAZOLIUM IONIC LIQUID AND SOLVENT WITH HIGH BOILING POINT AND BATTERIES COMPRISING SAME FACTORIAL INC. (US) 2025-03-06 — — WO claimed
WO-2025049222-A1 ELECTROLYTE COMPRISING CYCLIC QUATERNARY AMMONIUM IONIC LIQUID AND SOLVENT WITH HIGH BOILING POINT AND BATTERIES COMPRISING SAME FACTORIAL INC. (US) 2025-03-06 — — WO claimed
CN-118879200-A High-permeability concrete surface reinforcing agent and preparation method thereof 中冶武汉冶金建筑研究院有限公司 2024-11-01 — — CN claimed
CN-118630340-A Polymer/inorganic composite solid proton membrane and preparation method and application thereof 扬州大学 2024-09-10 — — CN claimed
EP-4335246-A1 METHOD FOR A DIRECT RESISTANCE HEATING OR ANALYSIS OF A FILLING IN A PROCESS DEVICE Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-03-13 — — EP claimed
CN-115678494-B High-temperature-resistant silicone adhesive and preparation method thereof 宁波聚力新材料科技有限公司 2024-02-09 — — CN claimed
CN-114931942-B Preparation method and application of coal mine ventilation air methane combustion catalyst 太原理工大学 2024-01-19 — — CN claimed
CN-114437664-A Temperature-resistant oil-resistant acetone-removing type organosilicon sealant and preparation method and application thereof 广东高士高科实业有限公司 2022-05-06 — — CN claimed
CN-113956734-A Light easy-to-clean sand-in-water multicolor paint and preparation method and application thereof 嘉宝莉化工集团股份有限公司 2022-01-21 — — CN claimed
CN-113499860-A Efficient flotation method for smelting slag recycled by copper regeneration 江西新金叶实业有限公司 2021-10-15 — — CN claimed
EP-3281941-B1 PROCESS FOR PREPARING 2-(5-BROMO-4-(1-CYCLOPROPYLNAPHTHALEN-4-YL)-4H-1,2,4-TRIAZOL-3-YLTHIO)ACETIC ACID ZENTIVA KS (CZ) 2019-07-24 — — EP claimed
US-10196419-B2 Processes and intermediates for preparing anti-HIV agents GILEAD SCIENCES, INC. (US) 2019-02-05 — — US claimed
US-20180079773-A1 PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS GILEAD SCIENCES, INC. 2018-03-22 — — US claimed
WO-2015175521-A1 METHOD AND SYSTEM TO IMPROVE DRYING OF FLEXIBLE NANO-STRUCTURES TOKYO ELECTRON LIMITED (JP) 2015-11-19 — — WO claimed
US-20150325458-A1 METHOD AND SYSTEM TO IMPROVE DRYING OF FLEXIBLE NANO-STRUCTURES TOKYO ELECTRON LIMITED (JP) 2015-11-12 — — US claimed
US-5719300-A Process for the preparation of gestodene INDUSTRIALE CHIMICA S.R.L. (IT) 1998-02-17 — — US claimed
EP-0700926-A1 Process for the preparation of gestodene INDUSTRIALE CHIMICA S.r.l. (IT) 1996-03-13 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10196419-B2 Processes and intermediates for preparing anti-HIV agents SAMHD1, DHPS, LSS GAA 502/4885MGAM 926/4885SI 490/4885
US-20180079773-A1 PROCESSES AND INTERMEDIATES FOR PREPARING ANTI-HIV AGENTS SAMHD1, DHPS, LSS GAA 502/4885MGAM 926/4885SI 490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.