Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069023 | 0.79 | LTA4H (0.45) | PAX8ELANECA4ATML3MBTL1 | |
| SCHEMBL31498872 | 0.76 | ELANE (0.61) | PAX8ELANEATML3MBTL1TDP1 | |
| SCHEMBL22279923 | 0.75 | MAPT (0.44) | ELANEATML3MBTL1TDP1MAPT | |
| SCHEMBL6327053 | 0.75 | LTA4H (0.41) | PAX8ELANECA4ATML3MBTL1 | |
| SCHEMBL28756290 | 0.73 | CA4 (0.34) | ELANECA4ATML3MBTL1TDP1 | |
| SCHEMBL15356404 | 0.71 | L3MBTL1 (0.44) | PAX8ELANECA4ATML3MBTL1 | |
| SCHEMBL582104 | 0.70 | ELANE (0.46) | PAX8ELANECA4ATML3MBTL1 | |
| SCHEMBL347522 | 0.70 | TSHR (0.37) | PAX8ELANEATMTDP1MAPT | |
| SCHEMBL15843659 | 0.69 | MAPT (0.39) | ELANEATML3MBTL1TDP1MAPT | |
| SCHEMBL15843658 | 0.69 | MAPT (0.39) | ELANEATML3MBTL1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990669-A | Optically active α-amino aldehydes, process for the preparation thereof, and the use thereof for the stereoselective preparation of optically active β-amino alcohols | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0288764-B1 | OPTICALLY ACTIVE ALPHA-AMINO ALDEHYDES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN THE STEREOSELECTIVE PREPARATION OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| EP-0288764-A1 | Optically active alpha-amino aldehydes, processes for their preparation and their use in the stereoselective preparation of optically active beta-amino alcohols | BAYER AG (DE) | 1988-11-02 | — | — | EP | disclosed |