Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439324 | 0.79 | PNMT (0.53) | PNMTPPARGPPARAFPR2TSHR | |
| SCHEMBL3696588 | 0.79 | PNMT (0.41) | PNMTMAOBTSHRDPP4FAP | |
| SCHEMBL9781682 | 0.78 | KMO (0.56) | PNMTPPARGPPARAFPR2TSHR | |
| SCHEMBL2164417 | 0.76 | KDM6B (0.61) | PNMTPPARGPPARAFPR2TSHR | |
| SCHEMBL2164411 | 0.76 | KDM6B (0.61) | PNMTPPARGPPARAFPR2TSHR | |
| SCHEMBL434793 | 0.76 | SLC7A5 (0.55) | EGFRCTSS | |
| SCHEMBL4419129 | 0.75 | PNMT (0.53) | PNMTDPP4FAPDPP8DPP9 | |
| SCHEMBL9555774 | 0.75 | CYP1A2 (0.55) | — | |
| SCHEMBL1344165 | 0.75 | CYP1A2 (0.55) | — | |
| SCHEMBL5130053 | 0.75 | PNMT (0.58) | PNMTPPARGPPARAFPR2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428434-A2 | Compounds of aromatic amines and their enantiomers, process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1991-05-22 | — | — | EP | disclosed |