SCHEMBL4419129

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14135682	0.83	PNMT (0.37)	PNMTIDO1SLC6A3SLC6A2SLC6A4
	SCHEMBL8499284	0.82	PNMT (0.52)	PNMTIDO1TAAR1SLC6A3SLC6A2
	SCHEMBL26649158	0.81	PNMT (0.59)	PNMTIDO1TAAR1SLC6A3SLC6A2
	SCHEMBL19002457	0.78	KMO (0.48)	PNMTSLC6A3SLC6A2SLC6A4
	SCHEMBL4657515	0.77	SLC6A4 (0.52)	IDO1TAAR1SLC6A3SLC6A2SLC6A4
	SCHEMBL11565787	0.76	PNMT (0.49)	PNMTIDO1TAAR1SLC6A3SLC6A2
	SCHEMBL9841199	0.75	PNMT (0.45)	PNMTIDO1DPP4FAPDPP8
	SCHEMBL1442961	0.74	PNMT (0.56)	PNMTIDO1TAAR1SIGMAR1
	SCHEMBL29609180	0.72	IDO1 (0.52)	PNMTIDO1TAAR1SLC6A3SLC6A2
	SCHEMBL26004833	0.72	PNMT (0.64)	PNMTIDO1TAAR1SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.