Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CCNC | P24863 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841654 | 0.90 | MAPT (0.51) | KMT2ALMNAMAPTTHRBNPC1 | |
| Fluoride SCHEMBL9841278 | 0.90 | MAPT (0.57) | KMT2ALMNAMAPTNPC1POLB | |
| Fluoride SCHEMBL9842071 | 0.88 | RXRA (0.41) | KMT2ALMNAMAPTNPC1ALDH1A1 | |
| Fluoride SCHEMBL9841399 | 0.86 | NPC1 (0.57) | KMT2ALMNAMAPTNPC1POLB | |
| Fluoride SCHEMBL9841665 | 0.86 | NPC1 (0.57) | KMT2ALMNAMAPTNPC1POLB | |
| Fluoride SCHEMBL9841883 | 0.84 | MAPT (0.52) | KMT2AMAPTTHRBNPC1PLK1 | |
| Fluoride SCHEMBL9841436 | 0.84 | KMT2A (0.51) | KMT2ACCNCCDK8PDGFRBPDGFRA | |
| SCHEMBL17304609 | 0.83 | KMT2A (0.53) | KMT2ACCNCCDK8PDGFRBPDGFRA | |
| Fluoride SCHEMBL9841846 | 0.83 | KMT2A (0.62) | KMT2ACCNCCDK8PDGFRBPDGFRA | |
| Fluoride SCHEMBL9841343 | 0.82 | MAPT (0.44) | KMT2ALMNAMAPTTHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |