Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841343 | 0.93 | MAPT (0.44) | MAPTSMN1; SMN2NPC1CASP3RAB9A | |
| Fluoride SCHEMBL9841384 | 0.91 | MAPT (0.47) | MAPTSMN1; SMN2NPC1CASP3RAB9A | |
| Fluoride SCHEMBL9842071 | 0.91 | RXRA (0.41) | MAPTSMN1; SMN2NPC1CASP3RAB9A | |
| Fluoride SCHEMBL9841183 | 0.90 | THRB (0.47) | MAPTSMN1; SMN2NPC1CASP3RAB9A | |
| Fluoride SCHEMBL9841689 | 0.90 | THRB (0.47) | MAPTSMN1; SMN2NPC1CASP3RAB9A | |
| Fluoride SCHEMBL9841390 | 0.90 | THRB (0.47) | MAPTSMN1; SMN2NPC1CASP3RAB9A | |
| SCHEMBL17301235 | 0.85 | MAPT (0.55) | MAPTSMN1; SMN2NPC1CASP3RAB9A | |
| Fluoride SCHEMBL9841278 | 0.85 | MAPT (0.57) | MAPTSMN1; SMN2NPC1KMT2APOLB | |
| Fluoride SCHEMBL9841654 | 0.85 | MAPT (0.51) | MAPTSMN1; SMN2NPC1CASP3RAB9A | |
| Fluoride SCHEMBL9841586 | 0.85 | MAPT (0.45) | MAPTSMN1; SMN2NPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |