Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | ACR | P10323 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841672 | 0.93 | MAPT (0.43) | MAPTTHRBSMN1; SMN2NPC1KMT2A | |
| Fluoride SCHEMBL9841540 | 0.91 | MAPT (0.47) | MAPTTHRBSMN1; SMN2KMT2APRSS1 | |
| Fluoride SCHEMBL9841811 | 0.91 | RXRA (0.41) | MAPTNPC1RAB9AKMT2APRSS1 | |
| Fluoride SCHEMBL9841899 | 0.90 | PRSS1 (0.48) | MAPTTHRBSMN1; SMN2KMT2APRSS1 | |
| Fluoride SCHEMBL9841923 | 0.90 | PRSS1 (0.48) | MAPTTHRBSMN1; SMN2KMT2APRSS1 | |
| Fluoride SCHEMBL9841904 | 0.90 | PRSS1 (0.48) | MAPTTHRBSMN1; SMN2KMT2APRSS1 | |
| Fluoride SCHEMBL9841273 | 0.85 | MAPT (0.57) | MAPTSMN1; SMN2NPC1KMT2APRSS1 | |
| Fluoride SCHEMBL9841883 | 0.85 | MAPT (0.52) | MAPTTHRBSMN1; SMN2SENP8SENP7 | |
| SCHEMBL15693579 | 0.84 | MAPT (0.48) | MAPTTHRBSMN1; SMN2SENP8SENP7 | |
| Fluoride SCHEMBL9841436 | 0.84 | KMT2A (0.51) | MAPTTHRBNPC1KMT2APLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |