Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 8/20 | 0.46 |
| ▸ | THRA | P10827 | 7/20 | 0.46 |
| ▸ | RARA | P10276 | 2/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841899 | 1.00 | PRSS1 (0.48) | PRSS1ACRRARBMAPTSMN1; SMN2 | |
| Fluoride SCHEMBL9841904 | 1.00 | PRSS1 (0.48) | PRSS1ACRRARBMAPTSMN1; SMN2 | |
| Fluoride SCHEMBL9841540 | 0.99 | MAPT (0.47) | PRSS1ACRRARBMAPTSMN1; SMN2 | |
| Fluoride SCHEMBL9841672 | 0.95 | MAPT (0.43) | PRSS1ACRRARBMAPTSMN1; SMN2 | |
| Fluoride SCHEMBL9841586 | 0.90 | MAPT (0.45) | PRSS1ACRMAPTSMN1; SMN2THRB | |
| SCHEMBL9641055 | 0.87 | PRSS1 (0.59) | PRSS1ACRRARBMAPTSMN1; SMN2 | |
| Fluoride SCHEMBL9841811 | 0.86 | RXRA (0.41) | PRSS1MAPTMEN1KMT2AALDH1A1 | |
| Fluoride SCHEMBL9841390 | 0.86 | THRB (0.47) | PRSS1ACRRARBMAPTSMN1; SMN2 | |
| Fluoride SCHEMBL9841689 | 0.86 | THRB (0.47) | PRSS1ACRRARBMAPTSMN1; SMN2 | |
| Fluoride SCHEMBL9841183 | 0.86 | THRB (0.47) | PRSS1ACRRARBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |