Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 5/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843280 | 0.99 | LMNA (0.40) | LMNATYRALDH1A1HPGDHSD17B10 | |
| SCHEMBL1594594 | 0.74 | ALDH1A1 (0.53) | LMNATYRALDH1A1HPGDHSD17B10 | |
| SCHEMBL7236273 | 0.69 | CYP2C19 (0.39) | CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL7236577 | 0.69 | CYP2C19 (0.39) | GAACA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL7236567 | 0.69 | CYP2C19 (0.39) | GAACA1CA2CA9 | |
| SCHEMBL4908819 | 0.68 | TRPV1 (0.38) | LMNATYRALDH1A1HPGDHSD17B10 | |
| SCHEMBL28993182 | 0.67 | CA1 (0.39) | LMNATYRALDH1A1HPGDHSD17B10 | |
| SCHEMBL14142241 | 0.67 | ALDH1A1 (0.44) | ALDH1A1HPGDHSD17B10ALOX15TDP1 | |
| SCHEMBL6667896 | 0.67 | CA1 (0.39) | LMNATYRALDH1A1HPGDHSD17B10 | |
| SCHEMBL7355054 | 0.67 | CA1 (0.39) | LMNATYRALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041516-A | Macromolecules | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-08-20 | — | — | US | disclosed |