SCHEMBL6667896

SCHEMBL6667896

[CH2]c1ccc(C(C)(C)C)cc1O[SiH](C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
ALDH1A1 P00352 3/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTR1D P28221 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31
CYP2C19 P33261 2/20 0.31
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1594594 0.78 ALDH1A1 (0.53) CA1CA2CA9ALDH1A1HPGD
SCHEMBL14142241 0.78 ALDH1A1 (0.44) CA1CA2CA9ALDH1A1HPGD
SCHEMBL3378773 0.78 CA1 (0.39) CA1CA2CA9ALDH1A1HPGD
SCHEMBL2143927 0.78 CA1 (0.42) CA1CA2CA9ALDH1A1HPGD
SCHEMBL7355054 0.78 CA1 (0.39) CA1CA2CA9ALDH1A1HPGD
SCHEMBL28993182 0.78 CA1 (0.39) CA1CA2CA9ALDH1A1HPGD
SCHEMBL25265218 0.77 TDP1 (0.36) CA1CA2CA9ALDH1A1HPGD
SCHEMBL6760798 0.77 CYP2C19 (0.38) CA1CA2CA9ALDH1A1HPGD
SCHEMBL411850 0.77 CA1 (0.36) CA1CA2CA9ALDH1A1HPGD
SCHEMBL1793776 0.76 CA1 (0.38) CA1CA2CA9ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175151-A Useful for treating herpes group viruses SCHERING CORPORATION (US) 1992-12-29 US claimed
EP-0912571-B1 NAPHTHYRIDINES WHICH AFFECT IL-4 AND G-CSF SCHERING CORP (US) 2004-08-04 EP disclosed
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed
US-5942522-A 1-BENZYL-3-ETHOXYCARBONYL-4-DIMETHYLAMINOETHOXY-6-METHYL-2-(1H) -QUINOLINONE; ANTIVIRAL AGAINST DNA CONTAINING VIRUSES, SUCH AS HERPES GROUP VIRUSES SCHERING CORPORATION (US) 1999-08-24 US disclosed
US-5939431-A Naphthyridines which affect IL-4 and G-CSF SCHERING CORPORATION (US) 1999-08-17 US disclosed
EP-0912571-A2 NAPHTHYRIDINES WHICH AFFECT IL-4 AND G-CSF SCHERING CORPORATION (US) 1999-05-06 EP disclosed
WO-1997048368-A2 NAPHTHYRIDINES WHICH AFFECT IL-4 AND G-CSF SCHERING CORPORATION (US) 1997-12-24 WO disclosed
EP-0580812-A1 ANTI-TUMOR AND ANTI-PSORIATIC AGENTS SCHERING CORPORATION (US) 1994-02-02 EP disclosed
EP-0549729-A1 ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS SCHERING CORPORATION (US) 1993-07-07 EP disclosed
EP-0547145-A1 ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS SCHERING CORPORATION (US) 1993-06-23 EP disclosed
US-5190956-A Certain N-substituted 3-oximino-2,4-dioxoquinolin-2,4-(1H)diones useful for treating viral infections SCHERING CORPORATION (US) 1993-03-02 US disclosed
US-5179107-A Herpes SCHERING CORPORATION (US) 1993-01-12 US disclosed
US-5175151-A Useful for treating herpes group viruses SCHERING CORPORATION (US) 1992-12-29 US disclosed
WO-1992018507-A1 ANTI-TUMOR AND ANTI-PSORIATIC AGENTS SCHERING CORPORATION (US) 1992-10-29 WO disclosed
EP-0508792-A1 Anti-tumor and anti-psoriatic agents SCHERING CORPORATION (US) 1992-10-14 EP disclosed
WO-1992004326-A1 ANTIVIRAL COMPOUNDS SCHERING CORPORATION (US) 1992-03-19 WO disclosed
WO-1992004327-A1 ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS SCHERING CORPORATION (US) 1992-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 CA1 1373/4885CA2 2720/4885CA9 2095/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.