Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL8731868 | 0.71 | CA12 (0.37) | ESR1ESR2PDCD1CD274TDP1 | |
| SCHEMBL133408 | 0.69 | ESR1 (0.58) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| SCHEMBL20154795 | 0.68 | ESR1 (0.31) | ESR1ESR2PDCD1CD274 | |
| SCHEMBL2771196 | 0.65 | GSK3A (0.33) | — | |
| SCHEMBL10595996 | 0.64 | SRC (0.32) | — | |
| SCHEMBL4630558 | 0.63 | ESR1 (0.50) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| SCHEMBL25056741 | 0.62 | ESR1 (0.32) | ESR1ESR2PDCD1CD274 | |
| SCHEMBL2903592 | 0.62 | GSK3A (0.31) | — | |
| SCHEMBL9173832 | 0.62 | GABRA1 (0.46) | ESR1ESR2PDCD1CD274ALDH1A1 | |
| SCHEMBL503028 | 0.61 | IDO1 (0.56) | ESR1ESR2PDCD1CD274ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041516-A | Macromolecules | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-08-20 | — | — | US | disclosed |