Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842600 | 0.99 | HDAC4 (0.41) | HDAC4RXRARARBAGTR2RARA | |
| SCHEMBL9842585 | 0.99 | HDAC4 (0.41) | HDAC4RXRARARBAGTR2RARA | |
| SCHEMBL9842463 | 0.85 | MEN1 (0.43) | HDAC4RXRARARBRARARARG | |
| SCHEMBL9842848 | 0.84 | ITGB3 (0.39) | RARBRARARARGPPARGPPARA | |
| SCHEMBL9843144 | 0.84 | ITGB3 (0.39) | RARBRARARARGPPARGPPARA | |
| SCHEMBL9842691 | 0.84 | ITGB3 (0.39) | RARBRARARARGPPARGPPARA | |
| SCHEMBL9842508 | 0.84 | TP53 (0.36) | HDAC4RARBRARARARGKMT2A | |
| SCHEMBL9842634 | 0.83 | THRA (0.33) | HDAC4RXRAPPARGPPARA | |
| SCHEMBL9842669 | 0.82 | MEN1 (0.46) | HDAC4RARBRARAMEN1KMT2A | |
| SCHEMBL9842597 | 0.81 | HDAC4 (0.36) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |