SCHEMBL9842484

SCHEMBL9842484

CCCO[C@H]1CC[C@H](OC(=O)c2ccc(-c3ccc(F)cc3F)cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.40
PTGS2 P35354 1/20 0.40
SCN1A P35498 2/20 0.40
SCN2A Q99250 2/20 0.40
SCN3A Q9NY46 2/20 0.40
RARB P10826 1/20 0.40
MAPK14 Q16539 2/20 0.39
GCGR P47871 1/20 0.39
SERPINE1 P05121 1/20 0.39
ALDH1A1 P00352 2/20 0.38
HTT P42858 1/20 0.38
HTR2A P28223 1/20 0.38
GRM2 Q14416 1/20 0.38
MAOB P27338 2/20 0.38
F10 P00742 1/20 0.37
PPARG P37231 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
USP2 O75604 1/20 0.37
DHFR P00374 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9842716 0.93 RARB (0.43) KMT2APTGS2SCN1ASCN2ASCN3A
SCHEMBL9842249 0.92 RARB (0.47) KMT2APTGS2SCN1ASCN2ASCN3A
SCHEMBL11105516 0.88 SCN1A (0.48) KMT2ASCN1ASCN2ASCN3AMAPK14
SCHEMBL9842448 0.86 OXTR (0.41) KMT2APTGS2SCN1ASCN2ASCN3A
SCHEMBL9842399 0.86 OXTR (0.42) KMT2APTGS2SCN1ASCN2ASCN3A
SCHEMBL9842802 0.84 RARB (0.43) KMT2APTGS2SCN1ASCN2ASCN3A
SCHEMBL9842724 0.83 RARB (0.45) KMT2APTGS2SCN1ASCN2ASCN3A
SCHEMBL9842645 0.82 RARB (0.47) KMT2ASCN1ASCN2ASCN3ARARB
SCHEMBL10921631 0.81 FASN (0.44) RARBALDH1A1MAOBLMNAPDK2
SCHEMBL10921636 0.81 FASN (0.44) RARBALDH1A1MAOBLMNAPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed