Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.64 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842917 | 1.00 | PTGIR (0.64) | PTGIRCCNT1CDK9CCNA2CDK2 | |
| SCHEMBL9842920 | 0.87 | FAAH (0.54) | PTGIRTSHRLTB4RFAAH | |
| SCHEMBL9842871 | 0.87 | FAAH (0.54) | PTGIRTSHRLTB4RFAAH | |
| SCHEMBL9208677 | 0.79 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL8104423 | 0.79 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10 | |
| Water SCHEMBL9205505 | 0.77 | PTGIR (0.97) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9770992 | 0.76 | PTGIR (0.64) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9770984 | 0.76 | PTGIR (0.64) | PTGIRKDM4ETSHRHSD17B10 | |
| SCHEMBL9440886 | 0.73 | PTGIR (0.62) | PTGIRLTB4R | |
| SCHEMBL8104458 | 0.73 | PTGIR (0.67) | PTGIRRXRARXRBNR4A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | claimed |
| US-4983610-A | BLOOD PLATELET AGGREGATION INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-01-08 | — | — | US | claimed |
| US-4983610-A | BLOOD PLATELET AGGREGATION INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-01-08 | — | — | US | disclosed |