Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.54 |
| ▸ | DEGS1 | O15121 | 3/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081513 | 0.85 | TRPV1 (0.50) | NPC1RAB9AGAALMNATOP1 | |
| SCHEMBL8808773 | 0.85 | MAPK1 (0.57) | NPC1TP53RAB9ALMNAMAPT | |
| SCHEMBL8597230 | 0.85 | NPC1 (0.56) | SNCANPC1RAB9AMAPTPOLB | |
| SCHEMBL8811207 | 0.85 | TP53 (0.54) | NPC1TP53RAB9AMAPTMEN1 | |
| SCHEMBL892704 | 0.85 | HTT (0.54) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL9843014 | 0.81 | NPC1 (0.60) | NPC1TP53RAB9ALMNAMAPT | |
| SCHEMBL9843089 | 0.81 | RAB9A (0.64) | NPC1TP53RAB9AGAALMNA | |
| SCHEMBL8811109 | 0.81 | RAB9A (0.66) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL9842872 | 0.81 | HDAC3 (0.59) | NPC1RAB9AKDM4EHPGDMEN1 | |
| SCHEMBL5591039 | 0.80 | KMT2A (0.60) | NPC1RAB9ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |